SITAJAN D Tablet is a scientifically developed oral antidiabetic formulation that combines the DPP-4 inhibitor Sitagliptin with the well-established biguanide Metformin Hydrochloride (Extended Release). This dual-action therapy is designed for adult patients with type 2 diabetes mellitus who require better glycemic control than achieved by monotherapy alone. The combination of Sitagliptin and Metformin targets different physiological pathways to provide a synergistic effect in lowering both fasting plasma glucose (FPG) and postprandial glucose (PPG) levels.
Sitagliptin enhances the levels of active incretin hormones by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This action increases insulin secretion and decreases glucagon levels in a glucose-dependent manner, resulting in improved glycemic control with minimal risk of hypoglycemia. Metformin, on the other hand, works by decreasing hepatic glucose production and improving insulin sensitivity at the cellular level. The extended-release formulation of Metformin provides sustained glucose-lowering effects and enhances patient compliance by reducing gastrointestinal side effects.
SITAJAN D is especially beneficial for newly diagnosed patients, those with a history of insulin resistance, or individuals who have not achieved adequate control on Metformin alone. It is usually prescribed as a once-daily tablet, preferably with the evening meal, allowing for better control of nighttime and early morning glucose levels. Clinical studies have shown that the combination improves HbA1c levels significantly while maintaining a favorable weight and cardiovascular risk profile.
The tablet is produced by Bluepill Express in WHO-GMP, ISO, and USFDA-standard facilities using advanced granulation and coating technologies to ensure uniform drug distribution and extended drug release. Strict in-process controls and validated analytical methods are employed to verify each batch for identity, potency, purity, dissolution, stability, and absence of microbial or heavy metal contamination.
SITAJAN D is offered in a range of strengths to accommodate patient-specific treatment plans. Available combinations typically include Sitagliptin 50 mg or 100 mg with Metformin ER 500 mg, 850 mg, or 1000 mg. Each tablet is packaged in alu-alu or blister strips to preserve product integrity and shelf life. Bluepill Express offers custom labeling, international regulatory support, and logistics coordination to ensure timely delivery and market compliance.
Our regulatory dossier includes Certificate of Analysis (COA), Certificate of Pharmaceutical Product (COPP), Stability Data, MSDS, and Site Master File. The SITAJAN D brand is exported to major markets in Asia, the Middle East, Africa, and Latin America. It is a trusted solution in national diabetes care programs and by hospital procurement authorities seeking cost-effective and reliable anti-diabetic medications.
Bluepill Express prioritizes therapeutic efficacy, affordability, and global standards in all its manufacturing operations. The development of SITAJAN D aligns with our mission to offer accessible treatments for chronic diseases like diabetes, which is increasing in prevalence worldwide. Through strategic partnerships with international distributors and government tenders, we ensure uninterrupted availability of SITAJAN D in high-demand markets.
Description provided by Bluepill Express.
Sitagliptin 100 mg + Metformin Hydrochloride Extended Release 1000 mg
Type 2 diabetes mellitus glycemic control
DPP-4 inhibition by Sitagliptin; hepatic glucose reduction and enhanced insulin sensitivity by Metformin ER
Film-coated extended-release tablet
Once daily with the evening meal
WHO-GMP, ISO, USFDA compliant
Alu-alu or blister strips
Certificate of Analysis (COA), Certificate of Pharmaceutical Product (COPP), Stability Data, MSDS
Adults with type 2 diabetes inadequately controlled with Metformin alone or insulin resistance
Exported across Asia, Middle East, Africa, Latin America
Specifications
Sitagliptin Content
100 mg per tablet
Metformin Hydrochloride ER Content
1000 mg per tablet
Tablet Weight
Approx. 1.5 g
Tablet Dimensions
Standard film-coated pill size for oral administration
Shelf Life
Minimum 24 months when stored properly
Storage Conditions
Store below 30°C, protect from moisture and light
Packaging Type
Blister pack or alu-alu strip (10 tablets per strip)
Compliance Standards
Manufactured under GMP and validated quality systems
Batch Testing
Identity, potency, purity, dissolution, stability, microbial & heavy metals free
Manufacturer
Bluepill Express under Dr Precision label