GABASIGN 600 CAP - Dr Precision

GABASIGN 600 CAP is a high-strength capsule designed for the treatment of moderate to severe neuropathic pain and as adjunctive therapy in partial seizures. It contains Gabapentin 600 mg, a synthetic analogue of gamma-aminobutyric acid (GABA), which acts on the central nervous system by binding to voltage-gated calcium channels to modulate nerve signal transmission.

Developed by BluepillExpress, a globally recognized name in contract manufacturing, this formulation is produced under WHO-GMP and ISO-certified facilities, ensuring top-tier quality, safety, and compliance with international health authorities. GABASIGN 600 CAP is ideal for patients requiring higher dosage titration or maintenance of long-term neuropathic pain therapy.

Indications

Diabetic neuropathy

Postherpetic neuralgia

Adjunct therapy in partial seizures

Fibromyalgia (off-label)

Nerve pain from spinal injuries or shingles

Mechanism of Action

Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the CNS, reducing calcium influx into neurons and suppressing the release of excitatory neurotransmitters. This mechanism calms overactive nerves and provides relief from seizures and neuropathic pain.

Dosage & Administration

Recommended Dose: As directed by a physician; typically 300–900 mg taken 2–3 times daily

GABASIGN 600 CAP is used for patients who have been titrated to higher effective doses

Can be combined with other anticonvulsants or pain management drugs as part of a therapeutic regimen

Pharmacokinetics

Bioavailability: ~27–60%, decreases with dose

Tmax: ~3 hours

Half-life: 5–7 hours

Elimination: Renal, unchanged

No liver metabolism or protein binding