GABASIGN 800 CAP is a high-potency formulation containing Gabapentin 800 mg, developed to provide effective relief from chronic neuropathic pain and as an adjunctive therapy in the treatment of partial-onset seizures. Gabapentin is a structural analogue of GABA (gamma-aminobutyric acid) that modulates calcium channels in the nervous system to reduce nerve excitability and pain signaling.
This advanced pharmaceutical product is manufactured by BluepillExpress, a leading Indian third-party manufacturing company globally recognized for quality, regulatory excellence, and consistent supply chain execution. Each capsule is manufactured using advanced machinery and under rigorous quality control to meet global export requirements across regulated and semi-regulated markets.
Indications
Diabetic peripheral neuropathy
Postherpetic neuralgia
Partial seizures (adjunct therapy)
Fibromyalgia (off-label use)
Central pain syndrome
Nerve pain from spinal cord injuries or shingles
Mechanism of Action
Gabapentin acts by binding to the α2δ subunit of voltage-gated calcium channels in neurons, inhibiting the release of excitatory neurotransmitters such as glutamate, substance P, and norepinephrine. This helps reduce abnormal nerve firing and relieves neuropathic pain and seizures.
Dosage & Administration
Typical Dose Range: 300–3600 mg/day
GABASIGN 800 CAP is used in patients titrated to higher daily doses for stable long-term management
Dose to be taken as prescribed by a physician; often administered 2-3 times per day
Must not be stopped abruptly; gradual tapering is advised
Pharmacokinetics
Absorption: Dose-dependent (bioavailability decreases with increasing dose)
Tmax: 2–3 hours post-administration
Half-life: 5–7 hours
Elimination: Renal (unchanged)
Metabolism: Not significantly metabolized in the liver
Advantages of GABASIGN 800 CAP
High-dose capsule provides enhanced control of neuropathic symptoms
Non-sedative and non-addictive alternative to opioids
Suitable for patients who require less frequent dosing due to sustained concentration
Manufactured under GMP-certified facilities with complete quality assurance
Available for custom branding, bulk supply, and private labeling
Description provided by Bluepill Express.
Gabapentin 800 mg per capsule
Adjunct treatment of partial seizures and neuropathic pain management
Produced under WHO-GMP certified facilities by BluepillExpress
Meets regulatory requirements for export to regulated and semi-regulated markets
Modulates α2δ subunit of voltage-gated calcium channels reducing excitatory neurotransmitter release
Capsule for oral administration
Typically administered 2-3 times daily; suitable for high-dose stable long-term treatment
Dose-dependent absorption, Tmax 2-3 hours, half-life 5-7 hours, primarily renal elimination
Non-sedative, non-addictive alternative to opioids
Available for bulk supply, private labeling, and custom branding
Specifications
Capsule Content
800 mg Gabapentin
Indications
Diabetic peripheral neuropathy, Postherpetic neuralgia, Partial seizures adjunct therapy, Fibromyalgia (off-label), Central pain syndrome, Nerve pain from spinal cord injuries or shingles
Pharmacodynamics
Binds α2δ subunit on voltage-gated calcium channels inhibiting excitatory neurotransmitters
Bioavailability
Decreases with increasing dose (dose-dependent absorption)
Time to Peak Concentration (Tmax)
2 to 3 hours post-dose
Elimination Half-life
5 to 7 hours
Metabolism
Negligible hepatic metabolism
Excretion
Primarily renal, unchanged
Packaging Options
Bulk supply and customizable packaging available
Manufacturing Location
India (BluepillExpress)
Regulatory Compliance
WHO-GMP certified