Export Snapshot

Minimum order

1 Centimetre

HSN Code

On request

Origin

India

Lead time

On request

Port of dispatch

On request

Packaging

Standard export packaging

Shelf life / storage

As per product specification

Export markets served

Global markets

Ability to customise

As per OEM brief

Values shown are for Avd Pharmaceuticals Private Limited.

Company Avd Pharmaceuticals Private Limited

Avd Pharmaceuticals Private Limited

Manufacturer of Research Chemicals, Drug Substances, Drug Intermediates, Impurities, Specialty Chemicals, and Provider of Job Work & Toll Manufacturing Services for Pharmaceutical and Chemical Companies

Registered address: Pune, India. Industry: Chemicals, Dyes & Paints › Chemicals, Compounds & Formulations.

View profile →

Established

2022

Employees

11–30

GST

27AAXCA5614Q1ZS

IEC code

Not shared

Export markets

Global markets

Member since

Jun 2025

Turnover

$250,000 - $1 MM

Incorporation type

On request

Product details

N-Iodosuccinimide (NIS)

Product Summary:

• CAS Number: 516-12-1

• Molecular Formula: C4H4INO2

• Molecular Weight: 225.98 g/mol

• Synonyms: NIS

• Packaging: 5–25 kg HDPE jar

• Solubility: Soluble in acetonitrile, DCM

• Storage: Keep tightly sealed, protected from light

• Toxicity: Oxidizing; handle under ventilation

Applications:

• Electrophilic iodination

• Oxidizing agent in organic synthesis

• Cyclization and halogenation reagent

• Mild iodinating agent in organic synthesis
• Selective iodination of aromatic compounds and alkenes
• Halogenation reactions in pharmaceutical synthesis
• Preparation of iodo-substituted intermediates for agrochemicals\
• Oxidative transformations and rearrangement reactions

Description provided by Avd Pharmaceuticals Private Limited.

N-Iodosuccinimide (NIS)

Electrophilic iodinating agent, oxidizing agent, cyclizing reagent

Targets aromatic compounds, alkenes, and alkynes with high regioselectivity

Crystalline solid

Soluble in acetonitrile and dichloromethane (DCM)

Available in 5–25 kg HDPE jars

Tightly sealed, protected from light

Oxidizing agent; must be handled under ventilation

516-12-1

Specifications

Molecular Formula

C4H4INO2

Molecular Weight

225.98 g/mol

Physical State

Crystalline solid

Chemical Purity

High purity grade suitable for organic synthesis

Reactivity

Highly electrophilic iodinating and oxidizing properties

Storage Conditions

Store in a cool, dry place away from light

Handling Precautions

Use personal protective equipment and work in well-ventilated areas

Use cases

Category

chemicals > chemical reagents > iodine compounds

Primary application

Brand

Not specified

Product type

Product

Logistics & handling

Lead time

On request

Packaging

As per buyer requirement

Storage condition

As recommended by supplier

Origin

India

Form

As listed by supplier

Commercials Avd Pharmaceuticals Private Limited

Minimum order

1 Centimetre

Lead time

On request

Payment terms

As per negotiated commercial agreement

Frequently asked by buyers

How does N-Iodosuccinimide ensure regioselective iodination in aromatic compounds?

N-Iodosuccinimide acts as a mild electrophilic iodine donor that preferentially targets electron-rich positions on aromatic rings, enabling high regioselectivity without causing over-iodination or degradation of sensitive functional groups.

What solvents are compatible with N-Iodosuccinimide for effective iodination reactions?

N-Iodosuccinimide is highly soluble and commonly used in acetonitrile and dichloromethane (DCM), which provide optimal reaction media for efficient iodination and maintain reagent stability.

Can N-Iodosuccinimide be used safely for large-scale industrial synthesis?

Yes, NIS is available in bulk packaging (5–25 kg HDPE jars) and is suitable for large-scale industrial applications. However, due to its oxidizing nature, it must be handled with appropriate ventilation and safety measures.

What advantages does N-Iodosuccinimide offer over other iodinating agents?

NIS provides milder reaction conditions, higher selectivity, and fewer side reactions compared to other iodinating reagents. Its ability to act as both an oxidizing and cyclizing agent adds versatility in complex organic syntheses.

How should N-Iodosuccinimide be stored to maintain its efficacy?

To maintain its effectiveness, NIS should be stored tightly sealed in HDPE jars, protected from moisture and light to prevent decomposition and loss of reactivity.

Question not answered? Sellers typically reply within 24–48 hours. Ask a question

What similar products are available in this category?

Browse all →

GST VERIFIED

sodium carboxy methyl cellulose

My Business Hub

From $ 4.08

MOQ 25 MT

GST VERIFIED

refined iodized free flow fine salt – food grade export quality – 20-30 ppm iodine

Fakhri International

Price on request

MOQ 1 NOS

GST VERIFIED

anfira silver nitrate n/10 solution - lr - 500ml

Swasti Exports

From $ 27.21

MOQ 1 NOS

GST VERIFIED

anfira thiourea - lr - 500gm

Swasti Exports

From $ 12.47

MOQ 1 Centimetre

GST VERIFIED

rkd carboxymethyl cellulose sodium

R K D Pharmaceutical Llp

Price on request

MOQ 1 Centimetre

GST VERIFIED

anfira sodium acetate trihydrate - ar, acs - 500gm

Swasti Exports

From $ 3.91

MOQ 1 NOS

GST VERIFIED

anfira sodium azide - ar - 100gm

Swasti Exports

From $ 11.22

MOQ 1 NOS

GST VERIFIED

anfira sodium nitroprusside dihydrate - ar - 500gm

Swasti Exports

From $ 11.11

MOQ 1 NOS

More from Avd Pharmaceuticals Private Limited