Export Snapshot

Minimum order

1 Centimetre

HSN Code

On request

Origin

India

Lead time

On request

Port of dispatch

On request

Packaging

Standard export packaging

Shelf life / storage

As per product specification

Export markets served

Global markets

Ability to customise

As per OEM brief

Values shown are for Avd Pharmaceuticals Private Limited.

Company Avd Pharmaceuticals Private Limited

Avd Pharmaceuticals Private Limited

Manufacturer of Research Chemicals, Drug Substances, Drug Intermediates, Impurities, Specialty Chemicals, and Provider of Job Work & Toll Manufacturing Services for Pharmaceutical and Chemical Companies

Registered address: Pune, India. Industry: Chemicals, Dyes & Paints › Chemicals, Compounds & Formulations.

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Established

2022

Employees

11–30

GST

27AAXCA5614Q1ZS

IEC code

Not shared

Export markets

Global markets

Member since

Jun 2025

Turnover

$250,000 - $1 MM

Incorporation type

On request

Product details

Tetrabutylammonium Fluoride Trihydrate

Product Summary:

• CAS Number: 87749-50-6

• Molecular Formula: C16H36FNO3

• Molecular Weight: 309.46 g/mol

• Synonyms: TBAF trihydrate

• Packaging: 25 kg HDPE drum

• Solubility: Soluble in THF, acetonitrile

• Storage: Store in dry place, tightly sealed

• Toxicity: Avoid skin contact; corrosive

Applications:

• Deprotection of silyl groups

• Fluorination agent in synthesis

• Catalyst in organic transformations

• Fluoride source for desilylation reactions in organic synthesis
• Cleavage of silyl protecting groups
• Applied in nucleophilic fluorination
• Synthesis of fluorinated pharmaceuticals\
• Carbohydrate and nucleoside chemistry for selective deprotection

Description provided by Avd Pharmaceuticals Private Limited.

Tetrabutylammonium fluoride trihydrate (TBAF·3H2O)

87749-50-6

C16H36FNO3

309.46 g/mol

Trihydrate solid compound

Highly soluble in THF, acetonitrile

Mild fluoride source for desilylation and nucleophilic fluorination

25 kg HDPE drum

Store in a dry place, tightly sealed

Corrosive; avoid skin contact

Specifications

Purity

High purity suitable for research and industrial use

Water Content

Trihydrate form contains 3 molecules of water

Application Scope

Deprotection of silyl groups; fluorination agent; catalyst

Handling Precautions

Use gloves and protective equipment to avoid skin corrosion

Solvent Compatibility

Compatible with common organic solvents, including THF and acetonitrile

Shelf Life

Stable when stored under recommended conditions

Use cases

Category

chemicals > inorganic chemicals > inorganic salts > halide

Primary application

Brand

Not specified

Product type

Product

Logistics & handling

Lead time

On request

Packaging

As per buyer requirement

Storage condition

As recommended by supplier

Origin

India

Form

As listed by supplier

Commercials Avd Pharmaceuticals Private Limited

Minimum order

1 Centimetre

Lead time

On request

Payment terms

As per negotiated commercial agreement

Frequently asked by buyers

What solvents are preferred for dissolving Tetrabutylammonium fluoride trihydrate in industrial applications?

Tetrabutylammonium fluoride trihydrate exhibits high solubility in organic solvents such as tetrahydrofuran (THF) and acetonitrile, making these solvents preferred for industrial scale desilylation and nucleophilic fluorination reactions.

How does TBAF·3H2O improve desilylation efficiency compared to other fluoride sources?

The trihydrate form of TBAF provides a mild reaction environment allowing selective cleavage of silyl protecting groups while minimizing side reactions and degradation of sensitive substrates, enhancing overall desilylation efficiency.

What precautions should be taken when storing and handling TBAF·3H2O at a manufacturing site?

TBAF·3H2O should be stored in a dry, tightly sealed container to maintain stability and prevent moisture variation. Protective gloves and eyewear should be used because the compound is corrosive and can cause skin irritation.

Can Tetrabutylammonium fluoride trihydrate be used as a catalyst in organic transformations?

Yes, TBAF·3H2O serves as a catalyst in various organic transformations, especially those involving nucleophilic fluorination and facilitating the removal of silyl groups under mild conditions.

What packaging options are available for bulk supply of TBAF·3H2O for industrial users?

Tetrabutylammonium fluoride trihydrate is available in 25 kg HDPE drums suitable for industrial scale purchasing, ensuring ease of handling and maintaining reagent integrity during transport and storage.

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