Export Snapshot

Minimum order

1 unit

HSN Code

On request

Origin

India

Lead time

On request

Port of dispatch

On request

Packaging

Standard export packaging

Shelf life / storage

As per product specification

Export markets served

Global markets

Ability to customise

As per OEM brief

Values shown are for Avd Pharmaceuticals Private Limited.

Company Avd Pharmaceuticals Private Limited

Avd Pharmaceuticals Private Limited

Manufacturer of Research Chemicals, Drug Substances, Drug Intermediates, Impurities, Specialty Chemicals, and Provider of Job Work & Toll Manufacturing Services for Pharmaceutical and Chemical Companies

Registered address: Pune, India. Industry: Chemicals, Dyes & Paints › Chemicals, Compounds & Formulations.

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Established

2022

Employees

11–30

GST

27AAXCA5614Q1ZS

IEC code

Not shared

Export markets

Global markets

Member since

Jun 2025

Turnover

$250,000 - $1 MM

Incorporation type

On request

Product details

Description:
DFTA, or 2,4-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone, is a key intermediate in the synthesis of the antifungal drug Fluconazole. This compound is crucial in constructing the pharmacophore responsible for Fluconazole's antifungal activity. It possesses a triazole ring and fluorinated aromatic structure, which contribute to its high reactivity and selectivity in targeted synthesis pathways. DFTA is primarily used in API production under controlled environments due to its chemical sensitivity.

Product Summary:

• CAS Number: 86404-63-9

• Molecular Formula: C10H7F2N3O

• Molecular Weight: 223.18 g/mol

• Synonyms: Fluconazole intermediate

• Packaging: 25 kg fiber drum

• Solubility: Soluble in acetone, dichloromethane

• Storage: Store in a dry, cool environment

• Toxicity: Handle with care; may cause irritation

Applications:

• Intermediate in Fluconazole synthesis

• Research in triazole-based antifungals

Description provided by Avd Pharmaceuticals Private Limited.

2,4-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone

Key intermediate in Fluconazole antifungal drug synthesis

C10H7F2N3O

223.18 g/mol

Contains triazole ring and fluorinated aromatic group

Soluble in acetone and dichloromethane

25 kg fiber drum

Store in dry, cool environment

Used under controlled environments for API production

May cause irritation; handle with proper protective equipment

Specifications

CAS Number

86404-63-9

Synonyms

Fluconazole intermediate

Physical State

Solid (powder form)

Chemical Sensitivity

High; requires handling under controlled environment

Applications

API manufacturing of Fluconazole; research for triazole antifungal agents

Use cases

Category

healthcare > apis > api intermediate

Primary application

Brand

Not specified

Product type

Product

Logistics & handling

Lead time

On request

Packaging

As per buyer requirement

Storage condition

As recommended by supplier

Origin

India

Form

As listed by supplier

Commercials Avd Pharmaceuticals Private Limited

Minimum order

1 unit

Lead time

On request

Payment terms

As per negotiated commercial agreement

Frequently asked by buyers

What makes DFTA a critical intermediate in the production of Fluconazole?

DFTA’s unique structural features, including a dual fluorinated aromatic ring and a triazole moiety, are essential for forming the pharmacophore responsible for Fluconazole’s antifungal activity, enabling targeted reactivity and selectivity in the synthesis.

How should DFTA be stored to maintain its stability?

DFTA must be stored in a dry, cool environment to protect its chemical integrity and prevent degradation, due to its chemical sensitivity.

What solvents is DFTA soluble in for use in synthesis?

DFTA is soluble in organic solvents such as acetone and dichloromethane, which facilitates its application in various synthetic procedures.

What safety considerations should be taken when handling DFTA?

Due to its potential to cause irritation, DFTA should be handled with appropriate protective equipment in a controlled environment to avoid direct exposure.

Is DFTA used exclusively for Fluconazole production?

While primarily used in Fluconazole API synthesis, DFTA also serves as a valuable intermediate in the research and development of other triazole-based antifungal agents.

How is DFTA typically packaged for industrial use?

It is supplied in 25 kg fiber drums, suitable for bulk industrial handling and distribution.

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