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TOFISIGN 100 TAB - Dr Precision

Bluepill Express logo
Bluepill Express
Manufacturer, Contractor, Retailer, Brand Owner, Distributor, Exporter, Importer, Wholesaler, Startup — Surat, Gujarat, India · Replies in ~24–48 hours
FIEO Registered Export Ready
₹ 10.43 /Piece In stock
Inclusive of all taxes
MOQ: 1 Piece
Lead time: On request
GST invoice
Origin: India
Export ready
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Export Snapshot
Minimum order
1 Piece
HSN Code
On request
Origin
India
Lead time
On request
Port of dispatch
On request
Packaging
Standard export packaging
Shelf life / storage
As per product specification
Export markets served
Australia flag AU Canada flag CA United Kingdom flag GB United States flag US
Ability to customise
As per OEM brief
Values shown are for Bluepill Express.
Company Bluepill Express
Bluepill Express logo
Bluepill Express

Global Pharmaceutical Exporter | Trusted Third-Party Manufacturer for Medicines & Custom Compositions | BLUEPILL EXPRESS · View mutual connections with Dhruv

Registered address: Surat, India. Industry: Healthcare, Medical Supplies & Pharmaceuticals › Drugs & Pharmaceuticals.

FIEO Registered
View profile →
Established
2024
Employees
1–10
GST
24ABDFB4194J1ZE
IEC code
Not shared
Export markets
Australia flag AU Canada flag CA United Kingdom flag GB United States flag US
Member since
Jun 2025
Turnover
$250,000 - $1 MM
Incorporation type
On request
Product details

TOFISIGN 100 Tablet is a uniquely formulated anxiolytic medication that contains Tofisopam, a 2,3-benzodiazepine compound distinct from traditional benzodiazepines. Unlike conventional drugs in its class, Tofisopam is non-sedative, non-muscle relaxant, and does not impair cognitive functions—making it a preferred option for patients seeking relief from generalized anxiety disorder (GAD) and other psychosomatic disorders without experiencing drowsiness or dependency.


Produced by BluepillExpress, TOFISIGN 100 is manufactured in WHO-GMP and ISO-certified facilities with rigorous quality control systems in place. The tablet is formulated using precise granulation and compression technologies to ensure consistent drug content, optimal dissolution, and high oral bioavailability. Each batch is subjected to stringent HPLC assay validation, stability testing, and microbial load examination before being released for market supply.


Tofisopam acts on limbic brain structures and modulates dopamine pathways, promoting mental relaxation and emotional balance. However, it does not exhibit typical GABAergic activity seen in classical benzodiazepines. This pharmacodynamic profile ensures TOFISIGN does not cause sedation, dependency, or withdrawal symptoms, making it particularly suitable for long-term use in anxiety-prone individuals, professionals, and elderly patients who must maintain alertness.


TOFISIGN 100 is indicated for multiple conditions including:


Generalized Anxiety Disorder (GAD)


Psychogenic gastrointestinal issues such as IBS


Menopausal anxiety states


Stress-related palpitations and tension headaches


Co-administration in depressive disorders


One of the key advantages of TOFISIGN 100 is its dual action: it not only calms psychological stress but also improves somatic symptoms like gastrointestinal discomfort, muscular pain, and autonomic dysfunction. This makes it an ideal option for psychiatrists, neurologists, and general practitioners dealing with complex neuropsychological cases.


TOFISIGN 100 offers excellent patient compliance due to its once or twice daily dosing, lack of sedative effects, and minimal risk of habit formation. Patients typically report improved mood stability, better sleep architecture (without sedation), and reduced anxiety episodes within the first week of therapy.


Though Tofisopam has a favorable safety profile, clinicians are advised to monitor patients for rare side effects such as nausea, dizziness, or mild GI disturbances. It is contraindicated in patients with severe hepatic dysfunction and during pregnancy or lactation unless specifically advised. No significant interactions have been noted with SSRIs, SNRIs, or tricyclic antidepressants, allowing TOFISIGN 100 to be used as part of a combination therapy regimen when needed.


Each TOFISIGN 100 Tablet is packaged in tamper-evident blister strips or HDPE bottles, with full regulatory labeling, batch traceability, and product information inserts. BluepillExpress ensures all production is backed by the highest manufacturing standards, making TOFISIGN 100 suitable for both domestic use and global export to regulated and semi-regulated markets.

Description provided by Bluepill Express.

Tofisopam 100 mg per tablet

2,3-Benzodiazepine derivative (non-sedative anxiolytic)

Generalized Anxiety Disorder, Psychogenic Gastrointestinal Disorders (IBS), Menopausal Anxiety, Stress-related Palpitations, Tension Headaches, Adjunct in Depressive Disorders

WHO-GMP and ISO-certified third-party manufacturing under Dr Precision label

Non-sedative, non-muscle relaxant, no cognitive impairment, minimal dependency risk

Modulates limbic brain structures and dopamine pathways without typical GABAergic activity

Tamper-evident blister strips or HDPE bottles with full regulatory labeling

HPLC assay validation, stability testing, microbial load examination

Once or twice daily for enhanced patient compliance

Safe for long-term use, contraindicated in severe hepatic dysfunction and pregnancy without advice

Specifications
Product Name
TOFISIGN 100 Tablet
Manufacturer
BluepillExpress under Dr Precision brand
Active Substance
Tofisopam 100 mg
Tablet Type
Oral Tablet
Dosage Form
Solid oral dosage
Indications
Anxiety disorders, psychosomatic conditions, IBS, menopausal anxiety, stress-related palpitations, tension headaches, adjunct therapy in depression
Pharmacological Group
Anxiolytic (Non-traditional benzodiazepine)
Mode of Action
Limbic system modulation and dopamine pathway regulation, non-GABAergic
Manufacturing Standards
WHO GMP, ISO Certified
Packaging Options
Blister packs and HDPE bottles
Storage Conditions
Store in a cool, dry place away from direct sunlight
Shelf Life
As per regulatory approval and batch-specific stability data
Compatibility
No significant interaction with SSRIs, SNRIs, or tricyclic antidepressants
Contraindications
Severe hepatic dysfunction, pregnancy, lactation unless advised
Side Effects
Rare nausea, dizziness, mild gastrointestinal disturbances
Use cases
Category
healthcare > drugs and medicine > common disease medicines > pharmaceutical tablets
Primary application
Brand
Not specified
Product type
Product
Logistics & handling
Lead time
On request
Packaging
As per buyer requirement
Storage condition
As recommended by supplier
Origin
India
Form
As listed by supplier
Commercials Bluepill Express
Minimum order
1 Piece
Lead time
On request
Payment terms
As per negotiated commercial agreement
Frequently asked by buyers
How does TOFISIGN 100 differ from traditional benzodiazepines in its action?

TOFISIGN 100 contains Tofisopam, a 2,3-benzodiazepine derivative that does not exert sedative, muscle relaxant, or cognitive impairing effects commonly associated with traditional benzodiazepines. Instead, it modulates limbic brain structures and dopamine pathways without typical GABAergic activity, allowing effective anxiolysis without drowsiness or dependency.

What makes TOFISIGN 100 suitable for patients with irritable bowel syndrome?

TOFISIGN 100’s unique dual action not only alleviates psychological stress but also improves somatic symptoms including psychogenic gastrointestinal discomfort typical in IBS by modulating autonomic dysfunction and muscle tension without sedation.

Can TOFISIGN 100 be safely co-administered with antidepressants?

Yes, TOFISIGN 100 shows no significant pharmacological interactions with SSRIs, SNRIs, or tricyclic antidepressants, making it safe for use in combination therapy as advised by clinicians.

What quality standards does TOFISIGN 100 adhere to in manufacturing?

TOFISIGN 100 is manufactured by BluepillExpress under the Dr Precision label in WHO-GMP and ISO-certified facilities, employing advanced manufacturing technologies with comprehensive quality control including HPLC assay validation, stability, and microbial testing.

Is TOFISIGN 100 appropriate for long-term use in elderly patients?

Yes, due to its non-sedative profile, absence of dependency risk, and minimal cognitive impairment, TOFISIGN 100 is suitable for long-term use in elderly patients who require maintaining alertness and stable mood.

Question not answered? Sellers typically reply within 24–48 hours.

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TOFISIGN 100 TAB -  Dr Precision
TOFISIGN 100 TAB - Dr Precision
₹ 10.43 /Piece