Pyrrolizidine Alkaloids Extraction Plants Solvent Extraction Plant
Sold by MECH O TECH LLP · Manufacturer, Brand Owner, Exporter, Importer, Women Entrepreneur, Startup · Mumbai, Maharashtra, India
Sold by MECH O TECH LLP · Manufacturer, Brand Owner, Exporter, Importer, Women Entrepreneur, Startup · Mumbai, Maharashtra, India
Importers · Distributors · Wholesalers
MECH O TECH LLP is a Manufacturer, Brand Owner, Exporter, Importer, Women Entrepreneur, Startup based in Mumbai Maharashtra India.
Manufacturer, Brand Owner, Exporter, Importer, Women Entrepreneur, Startup · Mumbai, Maharashtra, India
A Leader in Extraction and Distillation At Mechotech, our strength comes from our skilled and experienced team, led by Mr. Srinivasa Rao Kadali. He is one of our key partners, with a remarkable 23 years of experience in extraction units and over 27 years of expertise in the distillation and mechanical engineering field. His vast knowledge and hands-on experience make him a trusted name in the industry. Our entire team is made up of expert engineers and technicians, each with more than 15 years of experience. This wealth of knowledge ensures that we provide high-quality solutions that are both efficient and reliable. Whether it's extraction plants, distillation plants, or mechanical engineering projects, our team is dedicated to delivering excellent results on every job.
Registered address: Secunderabad, India. Industry: Chemicals, Dyes & Paints > Chemical Processing Equipment & Machinery.
Pyrrolizidine is a nitrogen-containing heterocyclic compound that serves as the backbone for pyrrolizidine alkaloids (PAs). These alkaloids are commonly found in certain plants and are known for their toxic effects on the liver. Nicotine, a naturally occurring alkaloid in tobacco plants (Nicotiana tabacum), is a derivative of pyridine and pyrrolidine. Chemical Structure & Properties Molecular Formula: C₇H₁₁N Structure: A bicyclic system containing a pyrrolidine ring fused to a piperidine ring. Derivatives: Pyrrolizidine alkaloids are oxygenated derivatives of pyrrolizidine. Natural Sources of Pyrrolizidine Alkaloids (PAs) Boraginaceae Family (e.g., Comfrey, Heliotropium) Asteraceae Family (e.g., Senecio, Eupatorium) Fabaceae Family (e.g., Crotalaria)
Toxicity & Health Risks
Hepatotoxicity (Liver Damage) – PAs are metabolized in the liver into toxic pyrrole derivatives, which cause DNA damage, liver fibrosis, and veno-occlusive disease (VOD).
Carcinogenic & Mutagenic Effects – Chronic exposure to PAs is linked to liver cancer in humans and animals.
Food & Herbal Contamination – PAs may contaminate honey, herbal teas, milk, and grains, posing health risks.
Regulatory Bodies (WHO, FDA, EFSA) set strict limits on PA exposure due to their toxicity.
Industrial & Pharmaceutical Relevance
Medicinal Plant Research – Some plants with PAs (like Comfrey) were historically used for wound healing and inflammation.
Pesticide Research – PAs serve as natural insect deterrents.
Chemical Synthesis – Pyrrolizidine derivatives are used in organic synthesis and alkaloid-based drug development.
Detoxification & Prevention Strategies
Avoid PA-containing herbal supplements unless certified PA-free.
Monitor PA contamination in food (especially honey and grains).
Breeding & Genetic Modification – Efforts to develop PA-free plant varieties.
Analytical Testing (HPLC, Mass Spectrometry) for PA detection in food and pharmaceuticals.
Description provided by MECH O TECH LLP.
| Molecular Formula of Target Alkaloids | C7H11N |
|---|---|
| Type of Alkaloids Extracted | Pyrrolizidine Alkaloids (oxygenated derivatives) |
| Input Plant Material | Leaves and roots of Comfrey, Senecio, Eupatorium, Crotalaria, and related species |
| Solvent Type | Organic solvents compatible with PA extraction (e.g., ethanol, methanol) |
| Processing Capacity | Customizable batch sizes from laboratory scale (liters) to industrial scale (tons) |
| Operating Temperature Range | Ambient to 60°C, optimized for solvent evaporation and PA stability |
| Automation Level | Semi-automatic to fully automated control systems |
| Safety Certifications | Complies with industrial chemical handling and toxic substance regulations |
| Power Requirements | Variable depending on plant scale and configurations |
| Installation Requirements | Requires chemical processing facility with proper ventilation and waste management |
| Category | Chemical Extraction Equipment > Solvent Extraction Plants > Alkaloid Extraction Systems |
|---|---|
| Primary application | Wholesale, distribution, and international sourcing |
| Brand | Not specified |
| Product type | Product |
| Lead time | On request |
|---|---|
| Packaging | As per buyer requirement |
| Storage condition | As recommended by supplier |
| Origin | India |
| Form | As listed by supplier |
| Minimum order | 1 Unit |
|---|---|
| Lead time | On request |
| Payment terms | As per negotiated commercial agreement. |
| Checkout type | enquiry |
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