NERVIGESIC-NT CAP is an advanced oral capsule developed to provide targeted and long-lasting relief from neuropathic pain and associated psychological symptoms. It contains a scientifically balanced combination of Pregabalin, a gamma-aminobutyric acid (GABA) analog, and Nortriptyline, a tricyclic antidepressant (TCA), offering both analgesic and antidepressant benefits in one powerful formulation.
The neuropathic pain pathway involves nerve damage, inflammation, and abnormal excitability of neurons. Pregabalin acts by binding to the α2δ subunit of voltage-gated calcium channels in the central nervous system, which reduces the release of pro-pain neurotransmitters like glutamate and substance P. This action directly decreases neuronal excitability and provides prompt relief from burning, tingling, and stabbing sensations that characterize chronic nerve pain.
Nortriptyline complements this mechanism by blocking the reuptake of norepinephrine and serotonin, enhancing the descending inhibitory pain pathways in the spinal cord. Additionally, it has mood-stabilizing and anti-anxiety properties, which make it beneficial in treating the depression and sleep disturbances often coexisting with chronic pain conditions. This dual effect makes NERVIGESIC-NT CAP highly effective for patients suffering from fibromyalgia, diabetic neuropathy, sciatica, post-herpetic neuralgia, or pain resulting from spinal injuries.
NERVIGESIC-NT CAP is particularly beneficial for patients who experience neuropathic symptoms with psychological overlay, such as anxiety or sleep disruption. Its extended-release profile ensures consistent blood concentration over 24 hours, reducing the need for multiple daily dosages. Patients report improved sleep quality, emotional stability, and a significant reduction in pain intensity after continued use.
Formulated and manufactured by Bluepill Express, NERVIGESIC-NT CAP meets international GMP, WHO, and ISO quality certifications, ensuring pharmaceutical-grade consistency in every batch. The raw materials are sourced from validated suppliers, and each capsule undergoes stringent quality checks for purity, dissolution, and shelf stability. With advanced manufacturing technologies, Bluepill Express ensures that the product is bioequivalent, stable, and delivers peak therapeutic benefits with minimal side effects.
The product is ideal for inclusion in neurology, orthopedics, diabetology, and internal medicine portfolios. It can be prescribed as a first-line or adjunct therapy in both acute and chronic neuropathic conditions. With its convenient once or twice daily dosing and tolerable side effect profile, NERVIGESIC-NT CAP offers improved compliance and clinical outcomes for long-term management.
Description provided by Bluepill Express.
Pregabalin and Nortriptyline
Dual action neuro-analgesic and antidepressant effect
Neuropathic pain, fibromyalgia, diabetic neuropathy, post-herpetic neuralgia, sciatica, spinal injury neuralgia, mood and sleep disturbances
Extended-release oral capsule
GMP, WHO, ISO certified by Bluepill Express
Pregabalin binds α2δ subunit of voltage-gated calcium channels; Nortriptyline inhibits norepinephrine & serotonin reuptake
Long-lasting pain relief, mood stabilization, improved sleep quality, enhanced compliance
Validated raw materials, purity and stability testing
First-line or adjunct therapy in neuropathic pain management
Specifications
Pregabalin Content
Exact mg dosage as per formulation (specific mg per capsule to be confirmed)
Nortriptyline Content
Exact mg dosage as per formulation (specific mg per capsule to be confirmed)
Capsule Type
Gelatin-based extended-release capsule
Shelf Life
Typically 24 months from manufacturing
Storage Conditions
Store below 25°C, protect from moisture and light
Packaging
Strip packaging with batch and expiry details
Compliance Certifications
GMP certified, WHO and ISO quality standards
Manufacturer
Bluepill Express
Country of Origin
To be specified by manufacturer
Pharmacological Class
Neuro-analgesic and tricyclic antidepressant combination