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3D-MPLA-4A

Name: 3D-MPLA-4A
Brand: chengdu gc biotech
SKU: 8618793
Availability: InStoreOnly

Sold by swasti exports · Manufacturer, Trader, Exporter, Importer · Vadodara, Gujarat, India

Price

Price on request

In stock

Minimum order: 1 unit

Export Snapshot

MOQ

1 unit

Lead time

On request

Packaging

Standard export packaging

Shelf life / longevity

As per product specification

HS Code

On request

Origin

India

Port of dispatch

On request

Export markets served

United States Minor Outlying Islands flag

Values shown are for swasti exports.

Compliance & Certifications

IEC Certificate

Suitable for

Importers · Distributors · Wholesalers

Vadodara Dispatch on request FIEO member

swasti exports

Manufacturer, Trader, Exporter, Importer · Vadodara, Gujarat, India

We are Merchant Exporter and supplying Chemicals, Agriculture products, Rices, spices, Kashmiri Saffron, Iranian saffron, Dates and so many products.

Registered address: Vadodara, India. Industry: Chemicals, Dyes & Paints > Chemical Industry Related Services.

View profile All products

Established

2020

Employees

1–10

GST

24AIXPB0733C1ZO

IEC code

AIXPB0733C

Export markets

GlobalLinker Member Since

Jul 2020

Turnover

100000 - 2500000.

Incorporation Type

On request

IEC Certificate FIEO

Product details

What are the specifications of this product?

Overview

Full Name: 3-O-deacylated-4'-monophosphoryl lipid A (3-DMPLA) Form: 4-acylated form, featuring a tetra-acyl carbon chain structure. Source: Derived from the Lipopolysaccharide (LPS) of Salmonella minnesota Re595.

Product Description

Specifically engineered for immunological research, this variant is a key molecular probe for deciphering the Structure-Activity Relationship (SAR) of TLR4 receptors.Compared to the potent hexa-acyl (6A) version, the 4A variant exhibits minimal activity in human immune cells and functions as a potential TLR4 antagonist. It holds significant promise as a therapeutic lead for autoimmune and allergic diseases.Quality level: Research grade

Description provided by swasti exports.

Specifications

Product Title	3D-MPLA-4A
Full Chemical Name	3-O-deacylated-4'-monophosphoryl lipid A (3-DMPLA)
Acylation State	4-acylated
Lipid Chain Structure	Tetra-acyl carbon chain structure
Source Organism	Salmonella minnesota Re595
Material Type	Lipopolysaccharide-derived lipid A derivative
Quality Level	Research grade
Target Receptor	TLR4
Research Area	Immunology, inflammatory signaling, receptor biology
Functional Profile	Low immunostimulatory activity

Use cases

Category	Research Chemicals > Immunology Reagents > TLR4 Ligands
Primary application	Wholesale, distribution, and international sourcing
Brand	chengdu gc biotech
Product type	Product

Logistics & handling

Lead time	On request
Packaging	As per buyer requirement
Storage condition	As recommended by supplier
Origin	India
Form	As listed by supplier

Commercials (this seller)

Minimum order	1 unit
Lead time	On request
Payment terms	As per negotiated commercial agreement.
Checkout type	enquiry

Buyer questions

Frequently asked by buyers

Common questions B2B buyers ask before sourcing 3D-MPLA-4A. Answers compiled from verified sellers' commercial terms and platform data.

Q: How does the 4-acylated 3D-MPLA-4A differ from hexa-acyl MPLA in TLR4 research?

A: The 4-acylated 3D-MPLA-4A has a tetra-acyl chain structure and shows minimal activity in human immune cells, while hexa-acyl MPLA is more potent. This makes the 4A variant more suitable for studying reduced TLR4 activation and receptor structure-activity relationships.

Q: Why is Salmonella minnesota Re595 used as the source for this lipid A derivative?

A: Salmonella minnesota Re595 is a well-characterized source of LPS-derived lipid A molecules, making it useful for producing defined analogs like 3D-MPLA-4A for reproducible immunological studies.

Q: What type of studies is 3D-MPLA-4A best suited for?

A: It is best suited for TLR4 signaling studies, receptor-binding analysis, structure-activity relationship (SAR) investigations, and research into immune modulation relevant to autoimmune and allergic disease pathways.

Q: Can 3D-MPLA-4A be used to evaluate TLR4 antagonism?

A: Yes. Because it exhibits minimal activity in human immune cells, it is often explored as a potential TLR4 antagonist or immune-response modulator in experimental settings.

Q: What makes this product valuable as a therapeutic lead?

A: Its reduced immunostimulatory activity and defined interaction profile with TLR4 make it a useful lead compound for researchers exploring therapies for autoimmune and allergic disorders.

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